Dr Cabot and Mr Hyde

1 Neuroscience Research Institute, University of California at Santa Barbara, Santa Barbara, California, United States of America, 2 Department of Molecular, Cellular and Developmental Biology, University of California at Santa Barbara, Santa Barbara, California, United States of America, 3 Kavli Institute of Theoretical Physics, University of California at Santa Barbara, Santa Barbara, California, United States of America, 4 Department of Computer Science, University of California at Santa Barbara, Santa Barbara, California, United States of America, 5 Department of Chemical Engineering, University of California at Santa Barbara, Santa Barbara, California, United States of America, 6 Department of Human Genetics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, United States of America, 7 Departments of Psychiatry, Molecular and Medical Pharmacology, the Semel Institute and the Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, United States of America, 8 Department of Mathematics, Jackson State University, Jackson, Mississippi, United States of America, 9 Applied Biosystems, Foster City, California, United States of America